Is palifermin a chemotherapy?

Is palifermin a chemotherapy?

Palifermin is used to decrease the chance of developing severe mucositis or to shorten the duration of severe mucositis in cancer patients receiving chemotherapy and radiation therapy, and undergoing autologous or allogeneic transplant. Palifermin is not a cancer treatment, but a supportive care medicine.

What is the success rate of allogeneic stem cell transplant?

The predicted rate of survival was 62 percent. In allogeneic bone marrow transplantation, a person’s blood-forming stem cells are eliminated and then replaced with new, healthy ones obtained from a donor or from donated umbilical cord blood.

How long does it take to recover from a stem cell transplant for leukemia?

Preventing Infection. It usually takes 3 to 12 months for your immune system to recover from your transplant.

What medications are given after stem cell transplant?

Doctors commonly prescribe antifungal medications to treat fungal infections in those who have recently had a stem cell or organ transplant. They include medications such as fluconazole, voriconazole, posaconazole, and amphotericin B.

When do you use palifermin?

Palifermin is used to help prevent or heal mouth sores and ulcers in people being treated with chemotherapy and stem cell treatment. Palifermin is used in people receiving chemotherapy to treat blood cancers (Hodgkin’s disease, multiple myeloma, leukemia). This medicine is not a treatment for the cancer itself.

How is palifermin administered?

The recommended dose of Kepivance is 60 mcg/kg/day, administered as an intravenous bolus injection for 3 consecutive days before and 3 consecutive days after myelotoxic therapy, for a total of 6 doses. Administer the first 3 doses prior to myelotoxic therapy.

How long can you live after allogeneic stem cell transplant?

Conditional on surviving the first 2 to 5 years after allogeneic blood or marrow transplantation (BMT), the 10-year overall survival approaches 80%. Nonetheless, the risk of late mortality remains higher than the age- and sex-matched general population for several years after BMT.

What are the side effects of epoetin alfa?

Epoetin alfa injection products may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• headache.
• joint or muscle aches, pain, or soreness.
• nausea.
• vomiting.
• weight loss.
• sores in the mouth.
• difficulty falling asleep or staying asleep.
• depression.