What is the success rate of trastuzumab emtansine?

What is the success rate of trastuzumab emtansine?

Estimated percentages of patients who would be free of invasive disease at 3 years were 88.3% in the T-DM1 group and 77.0% in the trastuzumab group.

What is ado-trastuzumab emtansine used for?

Ado-trastuzumab emtansine injection is used to treat a certain type of breast cancer that has spread to other parts of the body and has not improved or has worsened after treatment with other medications.

Is ado-trastuzumab emtansine chemo?

Kadcyla (ado-trastuzumab emtansine) is a new class of chemotherapy drug called an antibody-drug conjugate used to treat breast cancer.

What is the difference between trastuzumab and trastuzumab emtansine?

Trastuzumab alone stops growth of cancer cells by binding to the HER2 receptor, whereas trastuzumab emtansine undergoes receptor-mediated internalization into cells, is catabolized in lysosomes where DM1-containing catabolites are released and subsequently bind tubulin to cause mitotic arrest and cell death.

What is the success rate of Kadcyla?

The study was designed to measure disease-free survival, which is how long the patient stayed alive and cancer-free. After 3 years, the rate of disease-free survival was 88% in the Kadcyla group compared with 77% in the Herceptin group.

When do you use trastuzumab emtansine?

What Ado-Trastuzumab Emtansine Is Used For: As a single agent to treat HER2-positive, metastatic breast cancer who previously received trastuzumab and a taxane, separately or in combination. Patients should have either: Received prior therapy for metastatic disease, or.

Do you lose hair on Kadcyla?

Hair loss usually starts after your first or second treatment. It is almost always temporary, and your hair will usually grow back after treatment finishes.

How bad is Kadcyla?

Lung problems: Kadcyla may cause inflammation of the lungs, which can be life-threatening. Symptoms include trouble breathing, cough, tiredness, and fluid in the lungs. Liver problems: Kadcyla may cause severe liver problems, including liver failure.

Do you lose hair with Kadcyla?

Does Kadcyla weaken your immune system?

This treatment affects the immune system. This may cause inflammation in different parts of the body which can cause serious side effects. They could happen during treatment, or some months after treatment has finished. In some people, these side effects could be life threatening.

Does KADCYLA weaken your immune system?