What kind of disease does Marburg virus cause?

What kind of disease does Marburg virus cause?

Key facts 1 Marburg virus disease (MVD), formerly known as Marburg haemorrhagic fever, is a severe, often fatal illness in humans. 2 Rousettus aegyptiacus, fruit bats of the Pteropodidae family, are considered to be natural hosts of Marburg virus. 3 The Marburg virus causes severe viral haemorrhagic fever in humans.

How long does it take to get rid of Marburg virus?

Male survivors of Marburg virus disease should practice safer sexual practices and hygiene for 12 months from onset of symptoms or until their semen twice tests undetected (negative) for Marburg virus.

Where is the outbreak of Marburg hemorrhagic fever?

Outbreak Resources, Viral Hemorrhagic Fever (VHF) Information for Specific Groups, References… CDC scientists have spearheaded a small pilot project deep inside the forests of Uganda to track the movement of bats that carry the deadly Marburg virus, a close cousin to Ebola.

How old was the woman who died from Marburg?

A 40-year-old Dutch woman with a recent history of travel to Uganda was admitted to hospital in the Netherlands. Three days prior to hospitalization, the first symptoms (fever, chills) occurred, followed by rapid clinical deterioration. The woman died on the 10th day of the illness 11 12.

Who is at risk for Marburg hemorrhagic fever?

People who have close contact with African fruit bats, humans patients, or non-human primates infected with Marburg virus are at risk. Historically, the people at highest risk include family members and hospital staff who care for patients infected with Marburg virus and have not used proper barrier nursing techniques.

What kind of test is used for Marburg HF?

Antigen-capture enzyme-linked immunosorbent assay (ELISA) testing, virus isolation, polymerase chain reaction (PCR), and IgM- capture ELISA can be used to confirm a case of Marburg HF within a few days of symptom onset. The IgG-capture ELISA is appropriate for testing persons later in the course of disease or after recovery.

How long does it take for Marburg virus to spread?

Many patients develop severe haemorrhagic manifestations between 5 and 7 days, and fatal cases usually have some form of bleeding, often from multiple areas. Fresh blood in vomitus and faeces is often accompanied by bleeding from the nose, gums, and vagina.

How to know if you have Marburg haemorrhagic fever?

Severe watery diarrhoea, abdominal pain and cramping, nausea and vomiting can begin on the third day. Diarrhoea can persist for a week. The appearance of patients at this phase has been described as showing “ghost-like” drawn features, deep-set eyes, expressionless faces, and extreme lethargy.

When to use IgG capture ELISA for Marburg HF?

The IgG-capture ELISA is appropriate for testing persons later in the course of disease or after recovery. In deceased patients, immunohistochemistry, virus isolation, or PCR of blood or tissue specimens may be used to diagnose Marburg HF retrospectively. Treatment There is no specific treatment for Marburg hemorrhagic fever.