What protein makes up approximately 35 50 of total serum protein concentration?

What protein makes up approximately 35 50 of total serum protein concentration?

Albumin is the primary and most homogenous fraction, comprising 35% to 50% of total serum protein in animals. A key metabolic function of albumin is its role as a general binding and transport protein.

What does it mean if your albumin globulin ratio is high?

High A/G ratio: This can be a sign of disease in your liver, kidney, or intestines. It’s also linked to low thyroid activity and leukemia. If your doctor feels any of your levels are too high or low, you may need to have more precise blood or urine tests.

How do you differentiate albumin from globulin protein?

The most common protein in the blood is albumin, which prevents fluid from leaking out of the blood and also carries substances through the body. Almost all of the other proteins in the blood are globulins. Globulins are formed by the immune system and by the liver.

What happens if total protein is high?

A high total protein level could indicate dehydration or a certain type of cancer, such as multiple myeloma, that causes protein to accumulate abnormally. If the result of a total protein test is abnormal, further tests will be needed to identify which proteins are too high or too low.

What is the difference between globulin and albumin?

The main difference between albumin and globulin is that albumin is the key protein in the blood, which regulates the osmotic pressure of blood whereas globulin is the second abundant type of proteins in the blood and is important in liver function, blood clotting, and fighting infections.

What does high albumin and low globulin mean?

Low globulin levels can be a sign of liver or kidney disease. High levels may indicate infection, inflammatory disease or immune disorders. High globulin levels may also indicate certain types of cancer, such as multiple myeloma, Hodgkin’s disease, or malignant lymphoma.